Computational biologist / Bioinformatician

Position summary

  • Exciting career opportunity available in our Preclinical Development Dept. in Prague. Bring your diverse experiences and work within an exceptional, science-focused environment.
  • We are looking for a suitable candidate with specialization in computational biology approaches within the Preclinical department with the focus on biological drugs development.
  • You will work with an experienced team focused on the identification of predictive biomarkers and biomarkers for assessing drug efficacy  in the context of immuno-oncology approaches to shed light on various clinically relevant immuno-oncology areas.

Key activities and responsibilities

  • Application of relevant computational and bioinformatics methods to cancer genomic data (RNAseq, Nanostring and other advanced genetic datasets).
  • Computational analyses in the context of immuno-oncology.
  • Application of statistical approaches to biological problems.
  • Provide expertise to support the project team from early discovery to early clinical development.
  • Work in an integrated project team and consult with subject matter experts as necessary.

Competences, skills and qualification

  • Education in life science area, preferentially Bioinformatics, computational biology, molecular biology or similar with a PhD or Master degree.
  • Demonstrated familiarity with analysing and deciphering transcriptomic/genomic data, deriving systems biology-driven networks from omics data
  • Demonstrated previous experience with computational programming (e.g. R language/Python/MATLAB or others)
  • Demonstrated previous experience with analysis of publicly available cancer genetic expression datasets (especially TCGA datasets and GEOdatasets)
  • Skills in application of statistical approaches to biological problems (e.g. statistical testing, linear modelling)
  • Good communication skills
  • Highly collaborative spirit and willingness to work in collaboration with several different teams and clinicians
  • Fluent English (written and spoken)

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